Backup is a strategy, a plan and a process. I do the following:
(1) Image system/boot drives nightly
(2) Mirror application/file data across my machines multiple times daily
(3) Increment/save project files
(4) Mirror all data to RAID 5 server stores nightly
(5) Backup that data as much off site as possible – the new twist is the Time Warner upgraded speed to support 5 Mb/s uploads and currently uploading 4TB to Crashplan to see if that’s feasible for additional offsite storage. Initial backup obviously will take a couple of months but after that should keep speed.
(6) Own advanced undelete and recovery file utilities that support RAID recovery, removable media recovery etc. – these have saved my bacon as well as for colleagues several time.